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Histone Demethylase JARID1B Is Overexpressed in Osteosarcoma and Upregulates Cyclin D1 Expression via Demethylation of H3K27me3

JARID1B has been proven to be upregulated in many human malignancies and is correlated with tumor progression. However, its expression and clinical significance in osteosarcoma are still unclear. Thus, the aim of this study was to explore the effects of JARID1B in osteosarcoma tumorigenesis and deve...

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Detalles Bibliográficos
Autores principales: Wang, Wei, Zheng, Ke, Pei, Yi, Zhang, XiaoJing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cognizant Communication Corporation 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844678/
https://www.ncbi.nlm.nih.gov/pubmed/28492139
http://dx.doi.org/10.3727/096504017X14939809845080