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MicroRNA-519d-3p Inhibits Proliferation and Promotes Apoptosis by Targeting HIF-2α in Cervical Cancer Under Hypoxic Conditions

HIF-2α knockdown inhibits proliferation, arrests the cell cycle, and promotes apoptosis and autophagy under hypoxic conditions in cervical cancer. However, the upstream regulatory mechanism of HIF-2α expression is unclear. MicroRNAs (miRNAs) degrade target mRNAs by binding to the 3′-untranslated reg...

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Detalles Bibliográficos
Autores principales: Jiang, Lixia, Shi, Shaohua, Shi, Qiaofa, Zhang, Huijuan, Xia, Yu, Zhong, Tianyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cognizant Communication Corporation 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844701/
https://www.ncbi.nlm.nih.gov/pubmed/29321085
http://dx.doi.org/10.3727/096504018X15152056890500