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Downregulation of SRC Kinase Signaling Inhibitor 1 (SRCIN1) Expression by MicroRNA-32 Promotes Proliferation and Epithelial–Mesenchymal Transition in Human Liver Cancer Cells

MicroRNAs play an important role in regulating gene expression by binding to the 3′-UTR of target mRNAs. In this study, we have made an attempt to assess the molecular mechanisms by which miR-32 suppresses the expression of SRCIN1, thereby leading to promotion of proliferation and epithelial–mesench...

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Detalles Bibliográficos
Autores principales: Chen, Ren, Liao, Jin-Yao, Huang, Jing, Chen, Wen-Li, Ma, Xiao-Jun, Luo, Xiao-Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cognizant Communication Corporation 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844739/
https://www.ncbi.nlm.nih.gov/pubmed/28550679
http://dx.doi.org/10.3727/096504017X14954923820137