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ClC5 Decreases the Sensitivity of Multiple Myeloma Cells to Bortezomib via Promoting Prosurvival Autophagy

Resistance to bortezomib (BZ) is the major problem that largely limits its clinical application in multiple myeloma treatment. In the current study, we investigated whether ClC5, a member of the chloride channel family, is involved in this process. The MTT assay showed that BZ treatment decreased ce...

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Detalles Bibliográficos
Autores principales: Zhang, Huimin, Pang, Yuhui, Ma, Chuanbao, Li, Jianying, Wang, Huaquan, Shao, Zonghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cognizant Communication Corporation 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844740/
https://www.ncbi.nlm.nih.gov/pubmed/28899456
http://dx.doi.org/10.3727/096504017X15049221237147