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ClC5 Decreases the Sensitivity of Multiple Myeloma Cells to Bortezomib via Promoting Prosurvival Autophagy
Resistance to bortezomib (BZ) is the major problem that largely limits its clinical application in multiple myeloma treatment. In the current study, we investigated whether ClC5, a member of the chloride channel family, is involved in this process. The MTT assay showed that BZ treatment decreased ce...
Autores principales: | Zhang, Huimin, Pang, Yuhui, Ma, Chuanbao, Li, Jianying, Wang, Huaquan, Shao, Zonghong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cognizant Communication Corporation
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844740/ https://www.ncbi.nlm.nih.gov/pubmed/28899456 http://dx.doi.org/10.3727/096504017X15049221237147 |
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