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Acute systemic LPS-exposure impairs perivascular CSF distribution in mice

BACKGROUND: The exchange of cerebrospinal (CSF) and interstitial fluid is believed to be vital for waste clearance in the brain. The sleep-dependent glymphatic system, which is comprised of perivascular flow of CSF and is largely dependent on arterial pulsatility and astrocytic aquaporin-4 (AQP4) ex...

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Detalles Bibliográficos
Autores principales: Manouchehrian, Oscar, Ramos, Marta, Bachiller, Sara, Lundgaard, Iben, Deierborg, Tomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844902/
https://www.ncbi.nlm.nih.gov/pubmed/33514389
http://dx.doi.org/10.1186/s12974-021-02082-6