Cargando…
Application of imiquimod-induced murine psoriasis model in evaluating interleukin-17A antagonist
BACKGROUND: Interleukin-17A (IL17A) is a proinflammatory cytokine critically involved in autoimmune diseases, and monoclonal antibodies of IL17A have been approved for clinical treatment of psoriasis. However, a usable psoriatic animal model has been always required for preclinical evaluation of IL1...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844923/ https://www.ncbi.nlm.nih.gov/pubmed/33509093 http://dx.doi.org/10.1186/s12865-021-00401-3 |