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Application of imiquimod-induced murine psoriasis model in evaluating interleukin-17A antagonist

BACKGROUND: Interleukin-17A (IL17A) is a proinflammatory cytokine critically involved in autoimmune diseases, and monoclonal antibodies of IL17A have been approved for clinical treatment of psoriasis. However, a usable psoriatic animal model has been always required for preclinical evaluation of IL1...

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Detalles Bibliográficos
Autores principales:	Li, Qingran, Liu, Weiping, Gao, Shidong, Mao, Yao, Xin, Yanfei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844923/ https://www.ncbi.nlm.nih.gov/pubmed/33509093 http://dx.doi.org/10.1186/s12865-021-00401-3

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