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Evolutionary conservation and divergence of the human brain transcriptome

BACKGROUND: Mouse models have allowed for the direct interrogation of genetic effects on molecular, physiological, and behavioral brain phenotypes. However, it is unknown to what extent neurological or psychiatric traits may be human- or primate-specific and therefore which components can be faithfu...

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Detalles Bibliográficos
Autores principales: Pembroke, William G., Hartl, Christopher L., Geschwind, Daniel H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844938/
https://www.ncbi.nlm.nih.gov/pubmed/33514394
http://dx.doi.org/10.1186/s13059-020-02257-z