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Bitter taste receptor agonists regulate epithelial two-pore potassium channels via cAMP signaling

BACKGROUND: Epithelial solitary chemosensory cell (tuft cell) bitter taste signal transduction occurs through G protein coupled receptors and calcium-dependent signaling pathways. Type II taste cells, which utilize the same bitter taste signal transduction pathways, may also utilize cyclic adenosine...

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Detalles Bibliográficos
Autores principales: Kohanski, Michael A., Brown, Lauren, Orr, Melissa, Tan, Li Hui, Adappa, Nithin D., Palmer, James N., Rubenstein, Ronald C., Cohen, Noam A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844973/
https://www.ncbi.nlm.nih.gov/pubmed/33509163
http://dx.doi.org/10.1186/s12931-021-01631-0