Stereorandomization as a Method to Probe Peptide Bioactivity

[Image: see text] Solid-phase peptide synthesis (SPPS) is usually performed with optically pure building blocks to prepare peptides as single enantiomers. Herein we report that SPPS using racemic amino acids provides stereorandomized (sr) peptides, containing up to billions of different stereoisomer...

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Detalles Bibliográficos
Autores principales: Siriwardena, Thissa N., Gan, Bee-Ha, Köhler, Thilo, van Delden, Christian, Javor, Sacha, Reymond, Jean-Louis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7845017/
https://www.ncbi.nlm.nih.gov/pubmed/33532575
http://dx.doi.org/10.1021/acscentsci.0c01135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7845017/
https://www.ncbi.nlm.nih.gov/pubmed/33532575
http://dx.doi.org/10.1021/acscentsci.0c01135

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