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Stereorandomization as a Method to Probe Peptide Bioactivity
[Image: see text] Solid-phase peptide synthesis (SPPS) is usually performed with optically pure building blocks to prepare peptides as single enantiomers. Herein we report that SPPS using racemic amino acids provides stereorandomized (sr) peptides, containing up to billions of different stereoisomer...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7845017/ https://www.ncbi.nlm.nih.gov/pubmed/33532575 http://dx.doi.org/10.1021/acscentsci.0c01135 |