Inhibition of platelet adhesion, thrombus formation, and fibrin formation by a potent αIIbβ3 integrin inhibitor from ticks

BACKGROUND: Ticks puncture the skin of their hosts and secrete saliva, containing antiplatelet proteins, into the blood. Here, we studied disagregin, a potent platelet‐inhibiting protein derived from the salivary glands of Ornithodoros moubata, an African soft tick. Whereas conventional αIIbβ3 antag...

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Detalles Bibliográficos
Autores principales: van den Kerkhof, Danique L., Nagy, Magdolna, Wichapong, Kanin, Brouns, Sanne L.N., Heemskerk, Johan W. M., Hackeng, Tilman M., Dijkgraaf, Ingrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles ‐ Thrombosis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7845065/
https://www.ncbi.nlm.nih.gov/pubmed/33537548
http://dx.doi.org/10.1002/rth2.12466

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7845065/
https://www.ncbi.nlm.nih.gov/pubmed/33537548
http://dx.doi.org/10.1002/rth2.12466

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