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Detecting factor XIa in immune globulin products: Commutability of international reference materials for traditional and global hemostasis assays

BACKGROUND: Activated coagulation factor XIa (FXIa) is an impurity and primary source of procoagulant activity in thrombosis‐implicated immune globulin (IG) products. Several assays, of varying quality and precision are used to assess FXIa‐like procoagulant activity in units relevant to their respec...

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Detalles Bibliográficos
Autores principales: Liang, Yideng, Jackson, Joseph W., Woodle, Samuel A., Surov, Stepan S., Parunov, Leonid A., Scott, Dorothy E., Weinstein, Mark, Lee, Timothy K., Ovanesov, Mikhail V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7845073/
https://www.ncbi.nlm.nih.gov/pubmed/33537546
http://dx.doi.org/10.1002/rth2.12467