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My personal mutanome: a computational genomic medicine platform for searching network perturbing alleles linking genotype to phenotype

Massive genome sequencing data have inspired new challenges in personalized treatments and facilitated oncological drug discovery. We present a comprehensive database, My Personal Mutanome (MPM), for accelerating the development of precision cancer medicine protocols. MPM contains 490,245 mutations...

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Detalles Bibliográficos
Autores principales: Zhou, Yadi, Zhao, Junfei, Fang, Jiansong, Martin, William, Li, Lang, Nussinov, Ruth, Chan, Timothy A., Eng, Charis, Cheng, Feixiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7845113/
https://www.ncbi.nlm.nih.gov/pubmed/33514395
http://dx.doi.org/10.1186/s13059-021-02269-3