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HEYL Regulates Neoangiogenesis Through Overexpression in Both Breast Tumor Epithelium and Endothelium

Blocking tumor angiogenesis is an appealing therapeutic strategy, but to date, success has been elusive. We previously identified HEYL, a downstream target of Notch signaling, as an overexpressed gene in both breast cancer cells and as a tumor endothelial marker, suggesting that HEYL overexpression...

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Detalles Bibliográficos
Autores principales: Han, Liangfeng, Korangath, Preethi, Nguyen, Nguyen K., Diehl, Adam, Cho, Soonweng, Teo, Wei Wen, Cope, Leslie, Gessler, Manfred, Romer, Lewis, Sukumar, Saraswati
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7845423/
https://www.ncbi.nlm.nih.gov/pubmed/33520697
http://dx.doi.org/10.3389/fonc.2020.581459