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Flucloxacillin bone and soft tissue concentrations assessed by microdialysis in pigs after intravenous and oral administration

AIMS: Flucloxacillin is commonly administered intravenously for perioperative antimicrobial prophylaxis, while oral administration is typical for prophylaxis following smaller traumatic wounds. We assessed the time, for which the free flucloxacillin concentration was maintained above the minimum inh...

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Detalles Bibliográficos
Autores principales: Bendtsen, Mathias A. F., Bue, Mats, Hanberg, Pelle, Slater, Josefine, Thomassen, Maja B., Hansen, Jakob, Søballe, Kjeld, Öbrink-Hansen, Kristina, Stilling, Maiken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Editorial Society of Bone & Joint Surgery 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7845458/
https://www.ncbi.nlm.nih.gov/pubmed/33448872
http://dx.doi.org/10.1302/2046-3758.101.BJR-2020-0250.R1