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Interferons and other cytokines, genetics and beyond in COVID-19 and autoimmunity

Interferons are the best antiviral agents in vitro against SARS-CoV-2 so far and genetic defects in their signaling cascade or neutralization of alfa-interferons by autoantibodies come with more severe COVID-19. However, there is more, as the SARS-CoV-2 dysregulates not only innate immune mechanisms...

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Detalles Bibliográficos
Autores principales: Opdenakker, Ghislain, Van Damme, Jo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7845543/
https://www.ncbi.nlm.nih.gov/pubmed/33563543
http://dx.doi.org/10.1016/j.cytogfr.2021.01.004