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Metabolic Reprogramming Induces Immune Cell Dysfunction in the Tumor Microenvironment of Multiple Myeloma

Tumor cells rewire metabolism to meet their increased nutritional demands, allowing the maintenance of tumor survival, proliferation, and expansion. Enhancement of glycolysis and glutaminolysis is identified in most, if not all cancers, including multiple myeloma (MM), which interacts with a hypoxic...

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Detalles Bibliográficos
Autores principales: Wu, Shaojie, Kuang, Huixian, Ke, Jin, Pi, Manfei, Yang, Dong-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7845572/
https://www.ncbi.nlm.nih.gov/pubmed/33520703
http://dx.doi.org/10.3389/fonc.2020.591342