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Allisartan isoproxil attenuates oxidative stress and inflammation through the SIRT1/Nrf2/NF-κB signalling pathway in diabetic cardiomyopathy rats

Allisartan isoproxil is a new nonpeptide angiotensin II receptor blocker (ARB) precursor drug that is used to treat hypertension and reduce the risk of heart disease. The present study explored the effects of allisartan isoproxil on diabetic cardiomyopathy (DCM) and revealed the roles of hyperglycae...

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Detalles Bibliográficos
Autores principales: Jin, Qinyang, Zhu, Qin, Wang, Kai, Chen, Mengli, Li, Xinli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7845586/
https://www.ncbi.nlm.nih.gov/pubmed/33495841
http://dx.doi.org/10.3892/mmr.2021.11854