Human Cytomegalovirus UL7, miR-US5-1, and miR-UL112-3p Inactivation of FOXO3a Protects CD34(+) Hematopoietic Progenitor Cells from Apoptosis

Human cytomegalovirus (HCMV) infection of myeloid lineage cells, such as CD34(+) hematopoietic progenitor cells (HPCs) or monocytes, results in the upregulation of antiapoptotic cellular proteins that protect the newly infected cells from programmed cell death. The mechanisms used by HCMV to regulat...

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Detalles Bibliográficos
Autores principales: Hancock, Meaghan H., Crawford, Lindsey B., Perez, Wilma, Struthers, Hillary M., Mitchell, Jennifer, Caposio, Patrizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7845589/
https://www.ncbi.nlm.nih.gov/pubmed/33408225
http://dx.doi.org/10.1128/mSphere.00986-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7845589/
https://www.ncbi.nlm.nih.gov/pubmed/33408225
http://dx.doi.org/10.1128/mSphere.00986-20

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