Structure-Guided Design of a Synthetic Mimic of an Endothelial Protein C Receptor-Binding PfEMP1 Protein

Structure-guided vaccine design provides a route to elicit a focused immune response against the most functionally important regions of a pathogen surface. This can be achieved by identifying epitopes for neutralizing antibodies through structural methods and recapitulating these epitopes by graftin...

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Detalles Bibliográficos
Autores principales: Barber, Natalie M., Lau, Clinton K. Y., Turner, Louise, Watson, Gareth, Thrane, Susan, Lusingu, John P. A., Lavstsen, Thomas, Higgins, Matthew K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7845591/
https://www.ncbi.nlm.nih.gov/pubmed/33408232
http://dx.doi.org/10.1128/mSphere.01081-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7845591/
https://www.ncbi.nlm.nih.gov/pubmed/33408232
http://dx.doi.org/10.1128/mSphere.01081-20

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