Atypical Divergence of SARS-CoV-2 Orf8 from Orf7a within the Coronavirus Lineage Suggests Potential Stealthy Viral Strategies in Immune Evasion

Orf8, one of the most puzzling genes in the SARS lineage of coronaviruses, marks a unique and striking difference in genome organization between SARS-CoV-2 and SARS-CoV-1. Here, using sequence comparisons, we unequivocally reveal the distant sequence similarities between SARS-CoV-2 Orf8 with its SAR...

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Detalles Bibliográficos
Autores principales: Neches, Russell Y., Kyrpides, Nikos C., Ouzounis, Christos A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7845636/
https://www.ncbi.nlm.nih.gov/pubmed/33468697
http://dx.doi.org/10.1128/mBio.03014-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7845636/
https://www.ncbi.nlm.nih.gov/pubmed/33468697
http://dx.doi.org/10.1128/mBio.03014-20

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