CRNKL1 Is a Highly Selective Regulator of Intron-Retaining HIV-1 and Cellular mRNAs

The HIV-1 Rev protein is a nuclear export factor for unspliced and incompletely spliced HIV-1 RNAs. Without Rev, these intron-retaining RNAs are trapped in the nucleus. A genome-wide screen identified nine proteins of the spliceosome, which all enhanced expression from the HIV-1 unspliced RNA after...

Descripción completa

Detalles Bibliográficos
Autores principales: Xiao, Han, Wyler, Emanuel, Milek, Miha, Grewe, Bastian, Kirchner, Philipp, Ekici, Arif, Silva, Ana Beatriz Oliveira Villela, Jungnickl, Doris, Full, Florian, Thomas, Marco, Landthaler, Markus, Ensser, Armin, Überla, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7845644/
https://www.ncbi.nlm.nih.gov/pubmed/33468685
http://dx.doi.org/10.1128/mBio.02525-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7845644/
https://www.ncbi.nlm.nih.gov/pubmed/33468685
http://dx.doi.org/10.1128/mBio.02525-20

Ejemplares similares