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CRNKL1 Is a Highly Selective Regulator of Intron-Retaining HIV-1 and Cellular mRNAs

The HIV-1 Rev protein is a nuclear export factor for unspliced and incompletely spliced HIV-1 RNAs. Without Rev, these intron-retaining RNAs are trapped in the nucleus. A genome-wide screen identified nine proteins of the spliceosome, which all enhanced expression from the HIV-1 unspliced RNA after...

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Detalles Bibliográficos
Autores principales:	Xiao, Han, Wyler, Emanuel, Milek, Miha, Grewe, Bastian, Kirchner, Philipp, Ekici, Arif, Silva, Ana Beatriz Oliveira Villela, Jungnickl, Doris, Full, Florian, Thomas, Marco, Landthaler, Markus, Ensser, Armin, Überla, Klaus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7845644/ https://www.ncbi.nlm.nih.gov/pubmed/33468685 http://dx.doi.org/10.1128/mBio.02525-20

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