Ranolazine as an Alternative Therapy to Flecainide for SCN5A V411M Long QT Syndrome Type 3 Patients

The prolongation of the QT interval represents the main feature of the long QT syndrome (LQTS), a life-threatening genetic disease. The heterozygous SCN5A V411M mutation of the human sodium channel leads to a LQTS type 3 with severe proarrhythmic effects due to an increase in the late component of t...

Descripción completa

Detalles Bibliográficos
Autores principales: Cano, Jordi, Zorio, Esther, Mazzanti, Andrea, Arnau, Miguel Ángel, Trenor, Beatriz, Priori, Silvia G., Saiz, Javier, Romero, Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7845660/
https://www.ncbi.nlm.nih.gov/pubmed/33519442
http://dx.doi.org/10.3389/fphar.2020.580481

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7845660/
https://www.ncbi.nlm.nih.gov/pubmed/33519442
http://dx.doi.org/10.3389/fphar.2020.580481

Ejemplares similares