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Use of Multivariable Mendelian Randomization to Address Biases Due to Competing Risk Before Recruitment

Background: Mendelian randomization (MR) provides unconfounded estimates. MR is open to selection bias when the underlying sample is selected on surviving to recruitment on the genetically instrumented exposure and competing risk of the outcome. Few methods to address this bias exist. Methods: We sh...

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Detalles Bibliográficos
Autores principales: Schooling, C. M., Lopez, P. M., Yang, Z., Zhao, J. V., Au Yeung, Shiu Lun, Huang, Jian V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7845663/
https://www.ncbi.nlm.nih.gov/pubmed/33519914
http://dx.doi.org/10.3389/fgene.2020.610852