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Use of Multivariable Mendelian Randomization to Address Biases Due to Competing Risk Before Recruitment
Background: Mendelian randomization (MR) provides unconfounded estimates. MR is open to selection bias when the underlying sample is selected on surviving to recruitment on the genetically instrumented exposure and competing risk of the outcome. Few methods to address this bias exist. Methods: We sh...
Autores principales: | Schooling, C. M., Lopez, P. M., Yang, Z., Zhao, J. V., Au Yeung, Shiu Lun, Huang, Jian V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7845663/ https://www.ncbi.nlm.nih.gov/pubmed/33519914 http://dx.doi.org/10.3389/fgene.2020.610852 |
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