Multiscale modeling shows that dielectric differences make Na(V) channels faster than K(V) channels

The generation of action potentials in excitable cells requires different activation kinetics of voltage-gated Na (Na(V)) and K (K(V)) channels. Na(V) channels activate much faster and allow the initial Na(+) influx that generates the depolarizing phase and propagates the signal. Recent experimental...

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Detalles Bibliográficos
Autores principales: Catacuzzeno, Luigi, Sforna, Luigi, Franciolini, Fabio, Eisenberg, Robert S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7845922/
https://www.ncbi.nlm.nih.gov/pubmed/33502441
http://dx.doi.org/10.1085/jgp.202012706

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7845922/
https://www.ncbi.nlm.nih.gov/pubmed/33502441
http://dx.doi.org/10.1085/jgp.202012706

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