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Multiscale modeling shows that dielectric differences make Na(V) channels faster than K(V) channels
The generation of action potentials in excitable cells requires different activation kinetics of voltage-gated Na (Na(V)) and K (K(V)) channels. Na(V) channels activate much faster and allow the initial Na(+) influx that generates the depolarizing phase and propagates the signal. Recent experimental...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Rockefeller University Press
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7845922/ https://www.ncbi.nlm.nih.gov/pubmed/33502441 http://dx.doi.org/10.1085/jgp.202012706 |