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Targeting the JAK/STAT pathway in solid tumors

Aberrant activation of signal transducer and activator of transcription (STAT) proteins is associated with the development and progression of solid tumors. However, as transcription factors, these proteins are difficult to target directly. In this review, we summarize the role of targeting Janus kin...

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Detalles Bibliográficos
Autores principales: Qureshy, Zoya, Johnson, Daniel E., Grandis, Jennifer R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7845926/
https://www.ncbi.nlm.nih.gov/pubmed/33521321