Hydroxychloroquine-mediated inhibition of SARS-CoV-2 entry is attenuated by TMPRSS2

Hydroxychloroquine, used to treat malaria and some autoimmune disorders, potently inhibits viral infection of SARS coronavirus (SARS-CoV-1) and SARS-CoV-2 in cell-culture studies. However, human clinical trials of hydroxychloroquine failed to establish its usefulness as treatment for COVID-19. This...

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Detalles Bibliográficos
Autores principales: Ou, Tianling, Mou, Huihui, Zhang, Lizhou, Ojha, Amrita, Choe, Hyeryun, Farzan, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7845965/
https://www.ncbi.nlm.nih.gov/pubmed/33465165
http://dx.doi.org/10.1371/journal.ppat.1009212

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7845965/
https://www.ncbi.nlm.nih.gov/pubmed/33465165
http://dx.doi.org/10.1371/journal.ppat.1009212

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