Reconstructing tumor evolutionary histories and clone trees in polynomial-time with SubMARine

Tumors contain multiple subpopulations of genetically distinct cancer cells. Reconstructing their evolutionary history can improve our understanding of how cancers develop and respond to treatment. Subclonal reconstruction methods cluster mutations into groups that co-occur within the same subpopula...

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Detalles Bibliográficos
Autores principales: Sundermann, Linda K., Wintersinger, Jeff, Rätsch, Gunnar, Stoye, Jens, Morris, Quaid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7845980/
https://www.ncbi.nlm.nih.gov/pubmed/33465079
http://dx.doi.org/10.1371/journal.pcbi.1008400

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7845980/
https://www.ncbi.nlm.nih.gov/pubmed/33465079
http://dx.doi.org/10.1371/journal.pcbi.1008400

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