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Reconstructing tumor evolutionary histories and clone trees in polynomial-time with SubMARine
Tumors contain multiple subpopulations of genetically distinct cancer cells. Reconstructing their evolutionary history can improve our understanding of how cancers develop and respond to treatment. Subclonal reconstruction methods cluster mutations into groups that co-occur within the same subpopula...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7845980/ https://www.ncbi.nlm.nih.gov/pubmed/33465079 http://dx.doi.org/10.1371/journal.pcbi.1008400 |