Epigenetic suppression of SLFN11 in germinal center B-cells during B-cell development

BACKGROUND: SLFN11 has recently been reported to execute cancer cells harboring replicative stress induced by DNA damaging agents. However, the roles of SLFN11 under physiological conditions remain poorly understood. Germinal center B-cells (GCBs) undergo somatic hypermutations and class-switch reco...

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Detalles Bibliográficos
Autores principales: Moribe, Fumiya, Nishikori, Momoko, Takashima, Tsuyoshi, Taniyama, Daiki, Onishi, Nobuyuki, Arima, Hiroshi, Sasanuma, Hiroyuki, Akagawa, Remi, Elloumi, Fathi, Takeda, Shunichi, Pommier, Yves, Morii, Eiichi, Takaori-Kondo, Akifumi, Murai, Junko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7846023/
https://www.ncbi.nlm.nih.gov/pubmed/33513156
http://dx.doi.org/10.1371/journal.pone.0237554

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7846023/
https://www.ncbi.nlm.nih.gov/pubmed/33513156
http://dx.doi.org/10.1371/journal.pone.0237554

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