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The coronavirus proofreading exoribonuclease mediates extensive viral recombination

Recombination is proposed to be critical for coronavirus (CoV) diversity and emergence of SARS-CoV-2 and other zoonotic CoVs. While RNA recombination is required during normal CoV replication, the mechanisms and determinants of CoV recombination are not known. CoVs encode an RNA proofreading exoribo...

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Detalles Bibliográficos
Autores principales: Gribble, Jennifer, Stevens, Laura J., Agostini, Maria L., Anderson-Daniels, Jordan, Chappell, James D., Lu, Xiaotao, Pruijssers, Andrea J., Routh, Andrew L., Denison, Mark R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7846108/
https://www.ncbi.nlm.nih.gov/pubmed/33465137
http://dx.doi.org/10.1371/journal.ppat.1009226