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Human physiomimetic model integrating microphysiological systems of the gut, liver, and brain for studies of neurodegenerative diseases

Slow progress in the fight against neurodegenerative diseases (NDs) motivates an urgent need for highly controlled in vitro systems to investigate organ-organ– and organ-immune–specific interactions relevant for disease pathophysiology. Of particular interest is the gut/microbiome-liver-brain axis f...

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Detalles Bibliográficos
Autores principales: Trapecar, Martin, Wogram, Emile, Svoboda, Devon, Communal, Catherine, Omer, Attya, Lungjangwa, Tenzin, Sphabmixay, Pierre, Velazquez, Jason, Schneider, Kirsten, Wright, Charles W., Mildrum, Samuel, Hendricks, Austin, Levine, Stuart, Muffat, Julien, Lee, Meelim Jasmine, Lauffenburger, Douglas A., Trumper, David, Jaenisch, Rudolf, Griffith, Linda G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7846169/
https://www.ncbi.nlm.nih.gov/pubmed/33514545
http://dx.doi.org/10.1126/sciadv.abd1707