Keratinocytes control skin immune homeostasis through de novo–synthesized glucocorticoids

Glucocorticoids (GC), synthesized by the 11β-hydroxylase (Cyp11b1), control excessive inflammation through immunosuppressive actions. The skin was proposed to regulate homeostasis by autonomous GC production in keratinocytes. However, their immunosuppressive capacity and clinical relevance remain un...

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Detalles Bibliográficos
Autores principales: Phan, Truong San, Schink, Leonhard, Mann, Jasmin, Merk, Verena M., Zwicky, Pascale, Mundt, Sarah, Simon, Dagmar, Kulms, Dagmar, Abraham, Susanne, Legler, Daniel F., Noti, Mario, Brunner, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7846173/
https://www.ncbi.nlm.nih.gov/pubmed/33514551
http://dx.doi.org/10.1126/sciadv.abe0337

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7846173/
https://www.ncbi.nlm.nih.gov/pubmed/33514551
http://dx.doi.org/10.1126/sciadv.abe0337

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