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Anterior thalamic nuclei deep brain stimulation inhibits mossy fiber sprouting via 3′,5′-cyclic adenosine monophosphate/protein kinase A signaling pathway in a chronic epileptic monkey model

BACKGROUND: Anterior thalamic nuclei (ATN) deep brain stimulation (DBS) is an effective method of controlling epilepsy, especially temporal lobe epilepsy. Mossy fiber sprouting (MFS) plays an indispensable role in the pathogenesis and progression of epilepsy, but the effect of ATN-DBS on MFS in the...

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Detalles Bibliográficos
Autores principales: Du, Ting-Ting, Chen, Ying-Chuan, Zhu, Guan-Yu, Liu, De-Feng, Liu, Yu-Ye, Yuan, Tian-Shuo, Zhang, Xin, Zhang, Jian-Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7846430/
https://www.ncbi.nlm.nih.gov/pubmed/33410631
http://dx.doi.org/10.1097/CM9.0000000000001302