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Targeted inhibition of myeloid-derived suppressor cells in the tumor microenvironment by low-dose doxorubicin to improve immune efficacy in murine neuroblastoma

BACKGROUND: High agglomeration of myeloid-derived suppressor cells (MDSCs) in neuroblastoma (NB) impeded therapeutic effects. This study aimed to investigate the role and mechanism of targeted inhibition of MDSCs by low-dose doxorubicin (DOX) to enhance immune efficacy in NB. METHODS: Bagg albino (B...

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Detalles Bibliográficos
Autores principales: Xu, Wei-Li, Shi, Bao-Jun, Li, Suo-Lin, Yu, Feng-Xue, Guo, Li-Na, Li, Meng, Hu, Zhi-Gang, Li, Gui-Xin, Zhou, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7846436/
https://www.ncbi.nlm.nih.gov/pubmed/33278092
http://dx.doi.org/10.1097/CM9.0000000000001234