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Intense remodeling of extracellular matrix within the varicose vein: the role of gelatinases and vascular endothelial growth factor

BACKGROUND: Increased blood pressure in the varicose veins (VV) can contribute to the overexpression of matrix metalloproteinases (MMPs), affecting the endothelium, smooth muscle, and extracellular matrix of the vein wall. Gelatinases (MMP-2 and MMP-9), hypoxia, and inflammation occurring in the VV...

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Detalles Bibliográficos
Autores principales: Horecka, Anna, Hordyjewska, Anna, Biernacka, Jadwiga, Dąbrowski, Wojciech, Zubilewicz, Tomasz, Malec, Agnieszka, Musik, Irena, Kurzepa, Jacek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7846537/
https://www.ncbi.nlm.nih.gov/pubmed/32594304
http://dx.doi.org/10.1007/s11845-020-02289-1