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Intense remodeling of extracellular matrix within the varicose vein: the role of gelatinases and vascular endothelial growth factor
BACKGROUND: Increased blood pressure in the varicose veins (VV) can contribute to the overexpression of matrix metalloproteinases (MMPs), affecting the endothelium, smooth muscle, and extracellular matrix of the vein wall. Gelatinases (MMP-2 and MMP-9), hypoxia, and inflammation occurring in the VV...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7846537/ https://www.ncbi.nlm.nih.gov/pubmed/32594304 http://dx.doi.org/10.1007/s11845-020-02289-1 |