Chimeric synthetic reference standards enable cross-validation of positive and negative controls in SARS-CoV-2 molecular tests

DNA synthesis in vitro has enabled the rapid production of reference standards. These are used as controls, and allow measurement and improvement of the accuracy and quality of diagnostic tests. Current reference standards typically represent target genetic material, and act only as positive control...

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Detalles Bibliográficos
Autores principales: Madala, Bindu Swapna, Reis, Andre L. M., Deveson, Ira W., Rawlinson, William, Mercer, Tim R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7846570/
https://www.ncbi.nlm.nih.gov/pubmed/33514761
http://dx.doi.org/10.1038/s41598-021-81760-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7846570/
https://www.ncbi.nlm.nih.gov/pubmed/33514761
http://dx.doi.org/10.1038/s41598-021-81760-0

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