Cargando…
Chimeric synthetic reference standards enable cross-validation of positive and negative controls in SARS-CoV-2 molecular tests
DNA synthesis in vitro has enabled the rapid production of reference standards. These are used as controls, and allow measurement and improvement of the accuracy and quality of diagnostic tests. Current reference standards typically represent target genetic material, and act only as positive control...
Autores principales: | Madala, Bindu Swapna, Reis, Andre L. M., Deveson, Ira W., Rawlinson, William, Mercer, Tim R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7846570/ https://www.ncbi.nlm.nih.gov/pubmed/33514761 http://dx.doi.org/10.1038/s41598-021-81760-0 |
Ejemplares similares
-
A universal and independent synthetic DNA ladder for the quantitative measurement of genomic features
por: Reis, Andre L. M., et al.
Publicado: (2020) -
Using synthetic chromosome controls to evaluate the sequencing of difficult regions within the human genome
por: Reis, Andre L. M., et al.
Publicado: (2022) -
Library adaptors with integrated reference controls improve the accuracy and reliability of nanopore sequencing
por: Gunter, Helen M., et al.
Publicado: (2022) -
Synthetic microbe communities provide internal reference standards for metagenome sequencing and analysis
por: Hardwick, Simon A., et al.
Publicado: (2018) -
Chiral DNA sequences as commutable controls for clinical genomics
por: Deveson, Ira W., et al.
Publicado: (2019)