Non-apoptotic enteroblast-specific role of the initiator caspase Dronc for development and homeostasis of the Drosophila intestine

The initiator caspase Dronc is the only CARD-domain containing caspase in Drosophila and is essential for apoptosis. Here, we report that homozygous dronc mutant adult animals are short-lived due to the presence of a poorly developed, defective and leaky intestine. Interestingly, this mutant phenoty...

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Detalles Bibliográficos
Autores principales: Lindblad, Jillian L., Tare, Meghana, Amcheslavsky, Alla, Shields, Alicia, Bergmann, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7846589/
https://www.ncbi.nlm.nih.gov/pubmed/33514791
http://dx.doi.org/10.1038/s41598-021-81261-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7846589/
https://www.ncbi.nlm.nih.gov/pubmed/33514791
http://dx.doi.org/10.1038/s41598-021-81261-0

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