Rosmarinic acid suppresses tau phosphorylation and cognitive decline by downregulating the JNK signaling pathway

Rosmarinic acid (RA), a polyphenol found in Lamiaceae herbs, is a candidate of preventive ingredients against Alzheimer’s disease (AD) as it potently suppresses the aggregation of amyloid β (Aβ); however, the effect of RA on tau phosphorylation and cognitive dysfunction remains unclear. The present...

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Detalles Bibliográficos
Autores principales: Yamamoto, So, Kayama, Tomoko, Noguchi-Shinohara, Moeko, Hamaguchi, Tsuyoshi, Yamada, Masahito, Abe, Keiko, Kobayashi, Shoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7846760/
https://www.ncbi.nlm.nih.gov/pubmed/33514742
http://dx.doi.org/10.1038/s41538-021-00084-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7846760/
https://www.ncbi.nlm.nih.gov/pubmed/33514742
http://dx.doi.org/10.1038/s41538-021-00084-5

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