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Rosmarinic acid suppresses tau phosphorylation and cognitive decline by downregulating the JNK signaling pathway
Rosmarinic acid (RA), a polyphenol found in Lamiaceae herbs, is a candidate of preventive ingredients against Alzheimer’s disease (AD) as it potently suppresses the aggregation of amyloid β (Aβ); however, the effect of RA on tau phosphorylation and cognitive dysfunction remains unclear. The present...
Autores principales: | Yamamoto, So, Kayama, Tomoko, Noguchi-Shinohara, Moeko, Hamaguchi, Tsuyoshi, Yamada, Masahito, Abe, Keiko, Kobayashi, Shoko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7846760/ https://www.ncbi.nlm.nih.gov/pubmed/33514742 http://dx.doi.org/10.1038/s41538-021-00084-5 |
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