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Synthetic promoters to induce immune-effectors into the tumor microenvironment

Harnessing the immune-system to eradicate cancer is becoming a reality in recent years. Engineered immune cells, such as chimeric antigen receptor (CAR) T cells, are facing the danger of an overt life-threatening immune response due to the ON-target OFF-tumor cytotoxicity and Cytokine Release Syndro...

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Detalles Bibliográficos
Autores principales: Greenshpan, Yariv, Sharabi, Omri, Ottolenghi, Aner, Cahana, Avishag, Kundu, Kiran, M. Yegodayev, Ksenia, Elkabets, Moshe, Gazit, Roi, Porgador, Angel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7846768/
https://www.ncbi.nlm.nih.gov/pubmed/33514819
http://dx.doi.org/10.1038/s42003-021-01664-7