Backbone-independent NMR resonance assignments of methyl probes in large proteins

Methyl-specific isotope labeling is a powerful tool to study the structure, dynamics and interactions of large proteins and protein complexes by solution-state NMR. However, widespread applications of this methodology have been limited by challenges in obtaining confident resonance assignments. Here...

Descripción completa

Detalles Bibliográficos
Autores principales: Nerli, Santrupti, De Paula, Viviane S., McShan, Andrew C., Sgourakis, Nikolaos G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7846771/
https://www.ncbi.nlm.nih.gov/pubmed/33514730
http://dx.doi.org/10.1038/s41467-021-20984-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7846771/
https://www.ncbi.nlm.nih.gov/pubmed/33514730
http://dx.doi.org/10.1038/s41467-021-20984-0

Ejemplares similares