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Backbone-independent NMR resonance assignments of methyl probes in large proteins

Methyl-specific isotope labeling is a powerful tool to study the structure, dynamics and interactions of large proteins and protein complexes by solution-state NMR. However, widespread applications of this methodology have been limited by challenges in obtaining confident resonance assignments. Here...

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Detalles Bibliográficos
Autores principales:	Nerli, Santrupti, De Paula, Viviane S., McShan, Andrew C., Sgourakis, Nikolaos G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7846771/ https://www.ncbi.nlm.nih.gov/pubmed/33514730 http://dx.doi.org/10.1038/s41467-021-20984-0

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